April 1938: A dust bowl farmstead in Dallam County, Texas, showing the desolation produced by the dust and wind on the countryside adding to the problems of the depression in the USA. (Photo by Three Lions/Getty Images)
A young African American Young cotton picker in Arkansas during the Depression.
Photograph by Bobby Doherty for TIME
Many people with depression or anxiety are being prescribed emotional support animals: dogs, cats, pigs, hedgehogs and, yes, iguanas.
ILLUSTRATION FOR TIME BY STEVEN BRAY
Does our treatment of depression cause more misery?
Horses can lapse into apparent depression when they lose a companion.
Gillian Laub for TIME
Gillian helped pull Sam Cila of Riverhead, N.Y., out of a deep depression after an IED in Iraq cost him his hand
RR Auction / Handout / Reuters
Two pistols found on the bodies of famed Depression-era outlaws Bonnie Parker and Clyde Barrow after they were killed by a posse in 1934 have sold at auction for a total of $504,000 in Nashua, N.H., Sept. 30, 2012.
A lateral X-Ray of the head of a 38-year-old man shows two Deep Brain Stimulation (DBS) leads with four electrodes attached to each implanted in the subcortical area of the brain called the thalamus. A little bit of current may calm the tremors of Parkinson’s disease, ease depression and epilepsy, and awaken those with terrible injuries.